ERN2 antibody (AA 491-505)

Catalog No. ABIN343042

Product Details anti-ERN2 Antibody

Target: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Binding Specificity: AA 491-505

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This ERN2 antibody is un-conjugated

Application: ELISA

Specificity: Human ERN2.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey (93%) Marmoset (87%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-QKRLQSPSKQAQPLD from an internal region of human ERN2 (NP_150296.3). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%), Monkey (93%), Marmoset (87%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:4000)

Usage: Peptide ELISA: antibody detection limit dilution 1:4000. Western Blot: Preliminary experiments gave an approx 37kD band in Human Duodenum, Pancreas and Placenta lysates after 0.3 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 107kD according to NP_150296.3. The 37kD band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies / lysates? Have any further splice variants / modified forms been reported?

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for ERN2

Target: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Alternative Name: ERN2 (ERN2 Products)

Synonyms: Ire1beta antibody, ire1b antibody, Ern1 antibody, Ire1 antibody, Ire1b antibody, IRE1-BETA antibody, IRE1b antibody, endoplasmic reticulum to nucleus signaling 2 antibody, endoplasmic reticulum (ER) to nucleus signalling 2 antibody, ERN2 antibody, ern2 antibody, Ern2 antibody

Background: Name/Gene ID: ERN2
Subfamily: IRE
Family: Protein Kinase

Synonyms: ERN2, ER to nucleus signalling 2, HIRE2p, Inositol-requiring protein 2, IRE1-BETA, Inositol-requiring 1 beta, IRE1 beta, IRE2, IRE1b

Gene ID: 10595

NCBI Accession: NP_150296

UniProt: Q76MJ5