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Serotonin Receptor 3A antibody (HTR3A) (1st Extracellular Domain) Primary Antibody

HTR3A Reactivity: Mouse IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN350031
$454.67
Plus shipping costs $45.00
100 μL
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  • Target
    Serotonin Receptor 3A (HTR3A)
    Binding Specificity
    • 15
    • 11
    • 10
    • 9
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    1st Extracellular Domain
    Reactivity
    • 73
    • 17
    • 11
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 65
    • 7
    • 1
    Rabbit
    Clonality
    • 72
    • 1
    Polyclonal
    Conjugate
    • 29
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Serotonin Receptor 3A antibody is un-conjugated
    Application
    • 49
    • 41
    • 14
    • 13
    • 11
    • 10
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Specificity
    Specific for 5HT3A receptor.
    Purification
    Whole serum
    Immunogen
    A synthetic peptide from the 1t extracellular domain of mouse 5HT3A receptor conjugated to an immunogenic carrier protein was used as the antigen. The peptide shares 86% identity with rat sequence.
  • Application Notes
    A dilution of 1: 300 to 1: 2000 is recommended.
    The optimal dilution should be determined by the end user.
    Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    Serotonin Receptor 3A (HTR3A)
    Alternative Name
    5-HT3A R (HTR3A Antibody Abstract)
    Synonyms
    MGC52789, HTR3A, 5-HT3, 5HT3R, HTR3, 5-HT-3, 5-HT3A, 5-HT3R, 5HT3, Htr3, 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic L homeolog, 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine (serotonin) receptor 3A, htr3a.L, HTR3A, Htr3a
    Background
    Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
    Subcellular location: Cell junction › synapse › postsynaptic cell membrane, Multi-pass membrane protein. Cell membrane, Multi-pass membrane protein.
    Tissue specificity: Expressed in central and peripheral neurons. Induction: By nerve growth factor in PC12 cells. Also known as: 5-HT3R, 5-HT-3, Serotonin receptor 3A, Htr3a, 5ht3, Htr3, Serotonin gated ion channel receptor.
    Pathways
    Synaptic Membrane
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