Arc antibody

Catalog No. ABIN350080

Product Details anti-Arc Antibody

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Reactivity: Human, Rat, Mouse

Host: Sheep

Clonality: Polyclonal

Conjugate: This Arc antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for Arg3.1/ARC.

Immunogen: A synthetic peptide from human Arg3.1 (ARC) conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Isotype: IgG

Application Details

Application Notes: Use at a concentration of 10-50 µg/ml.
The optimal working concentration should be determined by the end user.
Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for Arc

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Alternative Name: Arg3.1 (ARC) (Arc Products)

Synonyms: ARC antibody, arg3.1 antibody, Arc3.1 antibody, C86064 antibody, mArc antibody, Arg3.1 antibody, rg3.1 antibody, ARG3.1 antibody, activity regulated cytoskeleton associated protein antibody, activity-regulated cytoskeleton-associated protein antibody, activity regulated cytoskeletal-associated protein antibody, ARC antibody, arc antibody, Arc antibody

Background: Function: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.
Subcellular location: Cytoplasm, cytoskeleton. Endosome. Acrosome. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendrite. Cell projection, dendritic spine. Cell junction, synapse. Note=Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail. Also known as: Activity-regulated cytoskeleton-associated protein, Activity-regulated gene 3.1 protein homolog, Arg3.1/ARC,.