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Kir2.2 antibody (Cytoplasmic Domain)

KCNJ12 Reactivity: Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN350390
  • Target See all Kir2.2 (KCNJ12) Antibodies
    Kir2.2 (KCNJ12) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12))
    Binding Specificity
    • 8
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cytoplasmic Domain
    Reactivity
    • 26
    • 12
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Rat
    Host
    • 27
    • 1
    Rabbit
    Clonality
    • 27
    • 1
    Polyclonal
    Conjugate
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    This Kir2.2 antibody is un-conjugated
    Application
    • 22
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    Specific for KCNJ12.
    Cross-Reactivity
    Mouse, Rat
    Cross-Reactivity (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogen
    A synthetic peptide from the cytoplasmic domain of rat KCNJ12 (KCNJN1, Kir2.2, IRK2) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in mouse.
    Isotype
    IgG
    Top Product
    Discover our top product KCNJ12 Primary Antibody
  • Application Notes
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    Kir2.2 (KCNJ12) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12))
    Alternative Name
    KCNJ12 (KCNJ12 Products)
    Synonyms
    IRK-2 antibody, IRK2 antibody, KCNJN1 antibody, Kir2.2 antibody, Kir2.2v antibody, hIRK antibody, hIRK1 antibody, hkir2.2x antibody, kcnj12x antibody, Kir2.1 antibody, IRK antibody, KIR2.2 antibody, MB-IRK2 antibody, potassium voltage-gated channel subfamily J member 12 antibody, ATP-sensitive inward rectifier potassium channel 12 antibody, potassium inwardly-rectifying channel, subfamily J, member 12 antibody, KCNJ12 antibody, LOC746628 antibody, Kcnj12 antibody
    Background
    FUNCTION: Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. Tissue specificity: Highest level in cerebellum. Moderately found in kidney, forebrain and skeletal muscle. Not detected in uterus, liver and pancreas. Subcellular location: Membrane, Multi-pass membrane protein.,Inward Rectifier,ATP-sensitive inward rectifier potassium channel 12, Potassium channel, inwardly rectifying subfamily J member 12, Inward rectifier K(+) channel Kir2.2, Kir2.2v, IRK2, KCNJN1
    UniProt
    P52188
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