OMP antibody

Catalog No. ABIN350664

Product Details anti-OMP Antibody

Target: OMP (Olfactory Marker Protein (OMP))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OMP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Highly specific for mature olfactory neurons (including axon and terminals).

Cross-Reactivity: Mouse, Rat

Cross-Reactivity (Details): Other species have not yet been tested.

Purification: IgG

Immunogen: A synthetic peptide from rat Olfactory Marker Protein conjugated to blue carrier protein has been used as the antigen. The peptide is homologous in mouse.

Isotype: IgG

Application Details

Application Notes: IHC, WB. Use at a concentration of 5-10 μg,ml. The optimal dilution should be determined by the end user. For IHC, Zamboni's,4 % PFA fixatives are recommended.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for OMP

Target: OMP (Olfactory Marker Protein (OMP))

Alternative Name: OMP (OMP Products)

Background: Olfactory marker protein (OMP) is an abundant, 19- kDa, cytosolic protein that is almost exclusively expressed in mature, functioning, olfactory neurons but not in the neural precursor basal cells. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Its tissue-specific expression in the receptor cells together with the results of the mouse knockout studies show that OMP represents a novel modulatory component of the odor detection/signal transduction cascade. FUNCTION: May act as a modulator of the olfactory signal-transduction cascade. SUBUNIT: Interacts with BEX1 and BEX2. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Uniquely associated with mature olfactory receptor neurons. SIMILARITY: Belongs to the olfactory marker protein family.<||a href="http://senselab.med.yale.edu/senselab/ordb/" ><||/a><||a href="http://www.enzim.hu/hmmtop1.1/server/submit.html" > <||/a>,OMP,Olfactory neuronal-specific protein

UniProt: P08523