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Trpl antibody (4th Cytoplasmic Loop)

Trpl Reactivity: Drosophila melanogaster IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN351175
  • Target See all Trpl Antibodies
    Trpl (Transient Receptor Potential-Like (Trpl))
    Binding Specificity
    4th Cytoplasmic Loop
    Reactivity
    Drosophila melanogaster
    Host
    • 1
    Rabbit
    Clonality
    • 1
    Polyclonal
    Conjugate
    • 1
    This Trpl antibody is un-conjugated
    Application
    Immunohistochemistry (IHC), Western Blotting (WB)
    Specificity
    Specific for TRPL.
    Cross-Reactivity
    Drosophila melanogaster
    Cross-Reactivity (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogen
    A synthetic peptide from 4th cytoplasmic loop of drosophila TRPL (Transient receptor potential like protein) conjugated to blue carrier protein was used as the antigen.
    Isotype
    IgG
  • Application Notes
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    Trpl (Transient Receptor Potential-Like (Trpl))
    Alternative Name
    TRPL (Trpl Products)
    Synonyms
    CG1694 antibody, CG18345 antibody, DmTRPL antibody, Dmel\\CG18345 antibody, TRPL antibody, TrpL antibody, Trpl antibody, dTRPL antibody, dTrpL antibody, trp-l antibody, transient receptor potential-like antibody, trpl antibody
    Background
    FUNCTION: A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction. Required for vision in the dark and in dim light. Binds calmodulin. Trp and trpl act together in the light response, although it is unclear whether as heteromultimers or distinct units. Also forms a functional cation channel with trp-gamma. Activated by fatty acids, metabolic stress, inositols and GTP-binding proteins. SUBUNIT: Forms heteromultimers with trp-gamma and, to a lower extent, with trp. Interacts with FKBP59 in vivo and is found in the inaD signaling complex. SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. Note: In the dark, there is 20 fold more rhabdomeral trpl protein forming plasma membrane channels than in the light. In the light, the protein translocates to an intracellular compartment. Protein levels remain unchanged in light and dark conditions.,Drosophila TRP,Transient receptor potential like protein, Transient-receptor-potential-like protein
    UniProt
    P48994
    Pathways
    Sensory Perception of Sound, Phototransduction
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