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PRKAG1 antibody (Middle Region)

PRKAG1 Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN359117
  • Target See all PRKAG1 Antibodies
    PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
    Binding Specificity
    • 9
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 48
    • 23
    • 7
    Human, Mouse
    Host
    • 46
    • 2
    Rabbit
    Clonality
    • 45
    • 3
    Polyclonal
    Conjugate
    • 23
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRKAG1 antibody is un-conjugated
    Application
    • 37
    • 30
    • 13
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to AMPK gamma (PRKAG1).
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human PRKAG1.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PRKAG1 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
    Alternative Name
    AMPK gamma-1 Chain / AMPKg (PRKAG1 Products)
    Synonyms
    MGC68503 antibody, zgc:63896 antibody, wu:fa94d09 antibody, wu:fd12h04 antibody, AMPKG antibody, Prkaac antibody, Prkga1 antibody, AA571379 antibody, BB036179 antibody, protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog antibody, protein kinase, AMP-activated, gamma 1 non-catalytic subunit antibody, protein kinase AMP-activated non-catalytic subunit gamma 1 antibody, prkag1.S antibody, prkag1 antibody, PRKAG1 antibody, Prkag1 antibody
    Background
    PRKAG1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK.Synonyms: 5'-AMP-activated protein kinase subunit gamma-1, PRKAG1
    Gene ID
    5571, 5874
    UniProt
    P54619
    Pathways
    AMPK Signaling, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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