PPM1G antibody (Middle Region)

Catalog No. ABIN360762

Product Details anti-PPM1G Antibody

Target: PPM1G (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G))

Binding Specificity: Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPM1G antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Protein phosphatase 1G/PPM1G.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157~187 from the center region of Human PPM1G.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for PPM1G

Target: PPM1G (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G))

Alternative Name: Protein Phosphatase 1G / PPM1G (PPM1G Products)

Synonyms: AI385652 antibody, Fin13 antibody, PP2CG antibody, PP2CGAMMA antibody, PPP2CG antibody, protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform antibody, protein phosphatase, Mg2+/Mn2+ dependent 1G antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1G antibody, Ppm1g antibody, PPM1G antibody

Background: PPM1G is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.Synonyms: PP2C-gamma, PPM1C, Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, Protein phosphatase magnesium-dependent 1 gamma

Molecular Weight: 59271 Da

Gene ID: 5496, 9606

UniProt: O15355