CTDSP2 antibody (N-Term)

Catalog No. ABIN360802

Product Details anti-CTDSP2 Antibody

Target: CTDSP2 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 2 (CTDSP2))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTDSP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to CTDSP2.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CTDSP2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/100 - 1/250. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for CTDSP2

Target: CTDSP2 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 2 (CTDSP2))

Alternative Name: CTDSP2 (CTDSP2 Products)

Synonyms: fb16c04 antibody, wu:fb16c04 antibody, zgc:77714 antibody, MGC68415 antibody, CTDSP2 antibody, OS4 antibody, PSR2 antibody, SCP2 antibody, AI586070 antibody, D10Ertd73e antibody, OS-4 antibody, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 antibody, CTD small phosphatase 2 L homeolog antibody, CTD small phosphatase 2 antibody, ctdsp2 antibody, ctdsp2.L antibody, CTDSP2 antibody, Ctdsp2 antibody

Background: CTDSP2 is one of several small CTD phosphatases (SCP). It has been proposed that SCP activity is an evolutionarily conserved transcriptional regulator that acts globally to silence neuronal genes. In addition, expression of phosphatase CTDSP2 mRNA isenhanced in several cancer cell lines with amplification of the CTDSP2 and CDK4 genes, and CTDSP2 coamplifies with CDK4 in some primary sarcomas. CTDSP2 may contribute to the development of a subset of sarcomas.Synonyms: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2, NLI-interacting factor 2, Nuclear LIM interactor-interacting factor 2, Protein OS-4, SCP2, Small CTD phosphatase 2

Gene ID: 10106

NCBI Accession: NP_005721

UniProt: O14595

Pathways: ER-Nucleus Signaling