TRPM2 antibody

Catalog No. ABIN361540

Product Details anti-TRPM2 Antibody

Target: TRPM2 (Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Purification: Antigen Affinity

Immunogen: Partial peptide of Mouse Trpm2 (C-terminal region)

Application Details

Application Notes: ELISA: 1ug/ml. WB: 1-5ug/ml. IHC: 5-10ug/ml. ICC: 1-5ug/ml.

Restrictions: For Research Use only

Handling

Concentration: 0.25 mg/ml

Buffer: PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]

Preservative: ProClin

Storage: -20 °C

Target Details for TRPM2

Target: TRPM2 (Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))

Alternative Name: Trpm2 (TRPM2 Products)

Synonyms: EREG1 antibody, KNP3 antibody, LTRPC2 antibody, NUDT9H antibody, NUDT9L1 antibody, TRPC7 antibody, Trpm2-predicted antibody, TRPM2 antibody, si:ch73-263b18.1 antibody, 9830168K16Rik antibody, C79133 antibody, Trp7 antibody, Trrp7 antibody, transient receptor potential cation channel subfamily M member 2 antibody, transient receptor potential cation channel, subfamily M, member 2 antibody, transient receptor potential cation channel subfamily C member 7 antibody, TRPM2 antibody, Trpm2 antibody, trpm2 antibody, TRPC7 antibody

Background: Function: Nonselective, voltage-independentcation channel mediating sodium and calcium ion influx in response to oxidative stress.Extracellularcalcium passes through the channel and acts from the intracellularside as a positive regulator in channel activation.Activatedby ADP-ribose, nicotinamide adenine dinucleotide (NAD+), reactive nitrogen species and arachidonic acid. Inactivated by intracellularATP. Confers susceptibility to cell death following oxidative stress. Has ADP-ribose pyrophosphatase activity Tissue specificity: Widely expressed, with highest levels in lung, spleen, eye and brain Sequence similarities: Belongs to the transient receptor family. LTrpC subfamily. Contains 1 nudix hydrolase domain.

Gene ID: 28240