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Cofilin1/2 (CFL1/2) (pTyr88) antibody

CFL1/2 Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN362442
  • Target See all Cofilin1/2 (CFL1/2) Antibodies
    Cofilin1/2 (CFL1/2)
    Binding Specificity
    • 10
    • 2
    • 1
    pTyr88
    Reactivity
    Human, Mouse, Rat
    Host
    • 13
    Rabbit
    Clonality
    • 13
    Polyclonal
    Conjugate
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 6
    • 4
    • 4
    • 3
    • 1
    Immunohistochemistry (IHC)
    Specificity
    The antibody detects endogenous level of cofilin1/cofilin2 only when phosphorylated at tyrosine 88.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogen
    Peptide sequence around phosphorylation site of pTyr88 (A-T-Y (p) -E-T) derived from Human coflin1, cofilin2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    Isotype
    IgG
    Top Product
    Discover our top product CFL1/2 Primary Antibody
  • Application Notes
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Li, Ke, Li, Liu, Zhu, Li: "DGCR6L, a novel PAK4 interaction protein, regulates PAK4-mediated migration of human gastric cancer cell via LIMK1." in: The international journal of biochemistry & cell biology, Vol. 42, Issue 1, pp. 70-9, (2009) (PubMed).

  • Target
    Cofilin1/2 (CFL1/2)
    Alternative Name
    cofilin1/cofilin2 (CFL1/2 Products)
    Synonyms
    CFL antibody, cofilin 1 antibody, CFL1 antibody
    Background
    Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
    Molecular Weight
    19 kDa
    UniProt
    Q9Y281
    Pathways
    Tube Formation, CXCR4-mediated Signaling Events
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