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ABL1/2 antibody (AA 391-395)

ABL1/ABL2 Reactivity: Human, Mouse IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN363102
  • Target See all ABL1/2 (ABL1/ABL2) Antibodies
    ABL1/2 (ABL1/ABL2) (Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2))
    Binding Specificity
    • 12
    • 10
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 391-395
    Reactivity
    • 24
    • 24
    • 8
    • 1
    Human, Mouse
    Host
    • 24
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ABL1/2 antibody is un-conjugated
    Application
    • 7
    • 6
    • 6
    • 4
    • 3
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Specificity
    The antibody detects endogenous levels of total ABL1/2 protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen. Specificity/Sensitivity ABL1/2 (Ab-393/429) Antibody detects endogenous levels of total ABL1/2 protein.
    Immunogen
    Peptide sequence around AA 391-395, 427-431 (D-T-Y-T-A) derived from ABL1, 2 Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Isotype
    IgG
    Top Product
    Discover our top product ABL1/ABL2 Primary Antibody
  • Application Notes
    Western blotting: 1:500-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    ABL1/2 (ABL1/ABL2) (Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2))
    Alternative Name
    ABL1/2 (ABL1/ABL2 Products)
    Synonyms
    CABL antibody, ABLL antibody, cb272 antibody, ABL proto-oncogene 2, non-receptor tyrosine kinase antibody, c-abl oncogene 2, non-receptor tyrosine kinase antibody, ABL2 antibody, abl2 antibody
    Background
    Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
    Molecular Weight
    210 kDa
    NCBI Accession
    NP_001129, NP_005148
    UniProt
    P42684
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