PRDM1 antibody (AA 199-409)

Catalog No. ABIN363225

Product Details anti-PRDM1 Antibody

Target: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Binding Specificity: AA 199-409

Reactivity: Human, Mouse, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This PRDM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Specificity: Reacts with ~98 kDa BLIMP-1 from mouse, pig and human

Cross-Reactivity (Details): May cross reacts with the beta form (~80 kDa).

Purification: Purified (protein G)

Immunogen: A fragment of the mouse Blimp-1 (residues 199-409)

Clone: 3H2-E8

Isotype: IgG1

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- ELISA: 1/100 to 1/2000 - ICC/ IF: 1/50 to 1/100 - IHC: 1/200 -FC: 8 μg/mL (for 2 x 10E6 cells/mL) - WB: 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: , Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 6 months

Target Details for PRDM1

Target: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Alternative Name: B Lymphocyte-Induced Maturation Protein-1 (BLIMP-1) (PRDM1 Products)

Synonyms: GB11750 antibody, CG5249 antibody, Dmel\\CG5249 antibody, blimp-1 antibody, dBlimp-1 antibody, dBlimp1 antibody, Blimp-1 antibody, Blimp1 antibody, nrd antibody, prdm1 antibody, ubo antibody, wu:fb99c12 antibody, zgc:91885 antibody, MGC52536 antibody, PRDM1 antibody, blimp1 antibody, xblimp1 antibody, prdi-bf1 antibody, BLIMP1 antibody, PRDI-BF1 antibody, ZNFPR1A1 antibody, PR/SET domain 1 antibody, probable serine/threonine-protein kinase DDB_G0282963 antibody, CG5249 gene product from transcript CG5249-RF antibody, blimp-1 antibody, PR domain containing 1a, with ZNF domain antibody, PR domain 1 S homeolog antibody, B lymphocyte induced maturation protein 1 antibody, PR domain 1 antibody, PR domain containing 1, with ZNF domain antibody, PRDM1 antibody, LOC408295 antibody, Blimp-1 antibody, CpipJ_CPIJ007425 antibody, prdm1a antibody, prdm1.S antibody, prdm1 antibody, Prdm1 antibody

Background: Blimp-1 (B lymphocyte maturation protein-1) is a nuclear protein with five zinc fingers in its carboxy terminus.It is a transcriptional repressor that is both required and sufficient to trigger terminal differentiation of B lymphocytes and monocyte/macrophages.Blimp-1 is expressed in, and may be required for terminally differentiated epithelial cells, retinal neurons and other lineage cells.Blimp-1 has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression.

Gene ID: 639

UniProt: O75626

Pathways: Regulation of Muscle Cell Differentiation