ROBO4 antibody (Internal Region)

Catalog No. ABIN363597

Product Details anti-ROBO4 Antibody

Target: ROBO4 (Roundabout, Axon Guidance Receptor, Homolog 4 (ROBO4))

Binding Specificity: AA 200-300, Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ROBO4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with the 85 kDa and 107 kDa isoforms of the ROBO4 human protein

Cross-Reactivity (Details): Not tested in other species

Purification: Antigen affinity purified

Immunogen: Synthetic peptide made to an internal region of the human protein (within residues 200-300)

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- IHC - P : 5 μg/mL - WB : 1/500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.09 mg/mL

Buffer: Tris-citrate, phosphate, ( pH 7-8) buffer, Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

Target Details for ROBO4

Target: ROBO4 (Roundabout, Axon Guidance Receptor, Homolog 4 (ROBO4))

Alternative Name: Roundabout Homolog 4 (ROBO4) (ROBO4 Products)

Synonyms: ECSM4 antibody, MRB antibody, 1200012D01Rik antibody, AI593217 antibody, sc:d0823 antibody, wu:fa16f09 antibody, roundabout guidance receptor 4 antibody, roundabout, axon guidance receptor, homolog 4 (Drosophila) antibody, ROBO4 antibody, Robo4 antibody, robo4 antibody

Background: Roundabouts (ROBO) are cell-surface receptors that mediate repulsive signaling mechanisms at the central nervous system midline. However, ROBOs may also mediate attraction mechanisms in the context of vascular development. ROBO4 is a novel roundabout protein which is restricted in expression to endothelial cells in vitro and sites of angiogenesis in vivo.Because it is not expressed on normal endothelial cells, in vivo, it is a promising tumor endothelial marker.

Gene ID: 54538