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GSK3 alpha antibody (HRP)

GSK3a Reactivity: Human, Mouse, Rat WB Host: Mouse Monoclonal SBGSK3a2 HRP
Catalog No. ABIN371628
  • Target See all GSK3 alpha (GSK3a) Antibodies
    GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
    Reactivity
    • 104
    • 84
    • 66
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 116
    • 22
    • 2
    Mouse
    Clonality
    • 113
    • 29
    Monoclonal
    Conjugate
    • 76
    • 11
    • 10
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GSK3 alpha antibody is conjugated to HRP
    Application
    • 113
    • 65
    • 58
    • 21
    • 20
    • 16
    • 13
    • 13
    • 7
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Specificity
    This antibody is specific for GSK3 alpha.
    Characteristics
    Synonyms: Glycogen synthase kinase-3 alpha, GSK3A, GSK-3 alpha, Factor A
    Clone
    SBGSK3a2
    Isotype
    IgG2a
    Top Product
    Discover our top product GSK3a Primary Antibody
  • Application Notes
    Western Blot: 1/5000-1/10,000. Predicted Molecular Weight: 51 kDa.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    50 % Glycerol/50 % PBS, pH 7.4 without preservatives.
    Preservative
    Without preservative
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
    Alternative Name
    GSK3 alpha (GSK3a Products)
    Synonyms
    2700086H06Rik antibody, GSK3A antibody, GSK-3[a] antibody, GSK-3[b] antibody, GSK3 antibody, gsk3a antibody, xgsk3 antibody, glycogen synthase kinase 3 alpha antibody, glycogen synthase kinase 3 alpha b antibody, glycogen synthase kinase 3 alpha S homeolog antibody, GSK3A antibody, Gsk3a antibody, gsk3a antibody, gsk3ab antibody, gsk3a.S antibody, Bm1_31380 antibody
    Background
    Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily, GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis. GSK3 signaling is performed by two isoforms, GSK3 alpha and GSK3 beta. The two isoforms share 97 % sequence similarity within their catalytic domains. GSK3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.Synonyms: Factor A, GSK-3 alpha, GSK3A, Glycogen synthase kinase-3 alpha
    Gene ID
    2931
    UniProt
    P49840
    Pathways
    PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect
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