ZMYM2 antibody (AA 1250-1300)

Catalog No. ABIN372247

Product Details anti-ZMYM2 Antibody

Target: ZMYM2 (Zinc Finger, MYM-Type 2 (ZMYM2))

Binding Specificity: AA 1250-1300

Reactivity: Human, Rat, Mouse, Cow, Dog, Chicken, Monkey, Orang-Utan

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZMYM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody recognizes Zinc Finger Protein 198 (ZNF198) (ZMYM2).

Cross-Reactivity (Details): Species reactivity (expected):Bovine, Chicken, Dog, Monkey, Mouse, Orangutan and RatSpecies reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to the amino acids 1250-1300 of human Zinc finger protein 198.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 0.1-1.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for ZMYM2

Target: ZMYM2 (Zinc Finger, MYM-Type 2 (ZMYM2))

Alternative Name: ZMYM2 (ZMYM2 Products)

Synonyms: ZMYM2 antibody, ZNF198 antibody, fc07a10 antibody, wu:fc07a10 antibody, si:dkey-51d17.6 antibody, fim antibody, mym antibody, ramp antibody, scll antibody, zfp198 antibody, znf198 antibody, MGC83724 antibody, FIM antibody, MYM antibody, RAMP antibody, SCLL antibody, 5830413P05Rik antibody, Zfp198 antibody, Znf198 antibody, zinc finger MYM-type containing 2 antibody, zinc finger, MYM-type 2 antibody, zinc finger MYM-type containing 2 L homeolog antibody, ZMYM2 antibody, zmym2 antibody, zmym2.L antibody, Zmym2 antibody

Background: Zfp198 (zinc finger protein 198, also known as ZNF198 or Zinc finger MYM-type protein 2) is a transcription factor that contains 9 MYM-type zinc fingers. Zfp198 interacts with, and is modified by, SUMO1 and colocalises with PML to nuclear bodies. Zfp198 has also been shown to stabilise the LSD1-CoREST-HDAC1 complex on chromatin through its MYM-type zinc fingers. A chromosomal translocation resulting in a Zfp198-FGFR1 fusion is associated with stem cell leukemia lymphoma syndrome (SCLL). SCLL usually presents as a lymphoblastic lymphoma in association with a myeloproliferative disorder.Synonyms: FIM, Fused in myeloproliferative disorders protein, RAMP, Rearranged in atypical myeloproliferative disorder protein, ZNF198, Zinc finger MYM-type protein 2, Zinc finger protein 198

Gene ID: 7750

NCBI Accession: NP_001177893

UniProt: Q9UBW7