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ZMYM2 antibody (Zinc Finger, MYM-Type 2) (AA 1250-1300) Primary Antibody

ZMYM2 Reactivity: Human, Mouse, Rat, Chicken, Cow, Dog, Monkey, Orang-Utan IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN372247
$495.00
Plus shipping costs $45.00
50 μg
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days
  • Target
    ZMYM2
    Binding Specificity
    AA 1250-1300
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Reactivity
    Human, Mouse, Rat, Chicken, Cow, Dog, Monkey, Orang-Utan
    • 30
    • 24
    • 20
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This ZMYM2 antibody is un-conjugated
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    • 17
    • 13
    • 9
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Specificity
    This antibody recognizes Zinc Finger Protein 198 (ZNF198) (ZMYM2).
    Cross-Reactivity (Details)
    Species reactivity (expected):Bovine, Chicken, Dog, Monkey, Mouse, Orangutan and RatSpecies reactivity (tested):Human.
    Purification
    Immunoaffinity Chromatography.
    Immunogen
    Synthetic peptide corresponding to the amino acids 1250-1300 of human Zinc finger protein 198.
    Isotype
    IgG
  • Application Notes
    Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 0.1-1.0 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    ZMYM2
    Alternative Name
    ZMYM2 (ZMYM2 Antibody Abstract)
    Synonyms
    ZMYM2, ZNF198, fc07a10, wu:fc07a10, si:dkey-51d17.6, fim, mym, ramp, scll, zfp198, znf198, MGC83724, FIM, MYM, RAMP, SCLL, 5830413P05Rik, Zfp198, Znf198, zinc finger MYM-type containing 2, zinc finger, MYM-type 2, zinc finger MYM-type containing 2 L homeolog, ZMYM2, zmym2, zmym2.L, Zmym2
    Background
    Zfp198 (zinc finger protein 198, also known as ZNF198 or Zinc finger MYM-type protein 2) is a transcription factor that contains 9 MYM-type zinc fingers. Zfp198 interacts with, and is modified by, SUMO1 and colocalises with PML to nuclear bodies. Zfp198 has also been shown to stabilise the LSD1-CoREST-HDAC1 complex on chromatin through its MYM-type zinc fingers. A chromosomal translocation resulting in a Zfp198-FGFR1 fusion is associated with stem cell leukemia lymphoma syndrome (SCLL). SCLL usually presents as a lymphoblastic lymphoma in association with a myeloproliferative disorder.Synonyms: FIM, Fused in myeloproliferative disorders protein, RAMP, Rearranged in atypical myeloproliferative disorder protein, ZNF198, Zinc finger MYM-type protein 2, Zinc finger protein 198
    Gene ID
    7750
    NCBI Accession
    NP_001177893
    UniProt
    Q9UBW7
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