MEIS1 antibody (Internal Region)

Catalog No. ABIN375073

Product Details anti-MEIS1 Antibody

Target: MEIS1 (Meis Homeobox 1 (MEIS1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This MEIS1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to MEIS1.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-SEDITRSANLTDQ, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/32000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MEIS1

Target: MEIS1 (Meis Homeobox 1 (MEIS1))

Alternative Name: MEIS1 (MEIS1 Products)

Synonyms: meis antibody, 1323/07 antibody, 1422/04 antibody, CG17117 antibody, Dm-HTH antibody, Dmel\\CG17117 antibody, HTH antibody, Hth antibody, Meis1 antibody, P53 antibody, anon-EST:Liang-2.13 antibody, clone 2.13 antibody, dtl antibody, hth1 antibody, hth2 antibody, l(3)05745 antibody, l(3)86Ca antibody, cb224 antibody, id:ibd5078 antibody, meis1.1 antibody, wu:fb38b03 antibody, wu:fc02e11 antibody, wu:fd12a02 antibody, C530044H18Rik antibody, Evi8 antibody, Meis homeobox 1 antibody, Meis homeobox 1 S homeolog antibody, homothorax antibody, Meis homeobox 1 b antibody, MEIS1 antibody, meis1.S antibody, Meis1 antibody, hth antibody, meis1b antibody, meis1 antibody

Background: MEIS1 is a member of the TALE (three amino acid loop extension) family of homeodomain containing proteins. In addition to binding with other Hox proteins, MEIS1 also forms heterodimers with the ubiquitously expressed Pbx proteins, including Pbx1, Pbx2 and Pbx3, and these complexes contain distinct DNA binding specificities. MEIS1 is implicated in oncogenesis as it is overexpressed as a result of adjacent retroviral insertion in BHX2 myeloid leukemias. It plays an important role in megakaryocytic gene expression.Synonyms: Homeobox protein Meis1

Gene ID: 4211, 9606

UniProt: O00470

Pathways: Chromatin Binding