MMP1
Reactivity: Human
WB, ELISA, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Applications: ELISA - Quality tested , IHC-PS - Reported in literature , IHC-FS - Reported in literature , ICC , WB - Reported in literature , Multiplex - Reported in literature
Matrix metalloproteinases (MMPs) are a family of at least 20 structurally related, zinc-containing enzymes that have the ability to brea kDaown connective tissue. MMP-1 is also known as collagenase, fibroblast collagenase, and interstitial collagenase. MMP-1 has shown substrate specificity to collagens I, II, III, VII. VIII and X, aggrecan, versican, tenascin, casein, gelatin, α 1-antitrypsin, myelin basic protein, L-selectin, pro-TNF, IL-1 β, pro-MMP-2 and pro-MMP-9 directly and indirectly by activating other MMPs.