Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

FADD antibody

FADD Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 1A11 unconjugated
Catalog No. ABIN377014
  • Target See all FADD Antibodies
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Reactivity
    • 87
    • 61
    • 19
    • 18
    • 15
    Human
    Host
    • 98
    • 17
    Mouse
    Clonality
    • 94
    • 21
    Monoclonal
    Conjugate
    • 67
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FADD antibody is un-conjugated
    Application
    • 89
    • 50
    • 31
    • 15
    • 15
    • 15
    • 11
    • 9
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Specificity
    Human FADD
    Characteristics
    Mouse Anti-Human FADD-UNLB
    Purification
    Purified
    Immunogen
    Recombinant FADD
    Clone
    1A11
    Isotype
    IgG1
    Top Product
    Discover our top product FADD Primary Antibody
  • Application Notes
    • Applications: ELISA - Quality tested WB - Quality tested IP - Quality tested
    • Working Dilutions: ELISA Purified (UNLB) antibody 0.5 g/mL Immunoblotting HRP conjugate 1:4,000 - 1:8,000 Immunoprecipitation SEPH conjugate 40 L
    Sample Volume
    0,2 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.1 mg of purified immunoglobulin in 0.2 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Preservative
    Without preservative
    Handling Advice
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C
  • Target
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Alternative Name
    FADD (FADD Products)
    Synonyms
    MORT1 antibody, Mort1/FADD antibody, Mort1 antibody, TNFRSF6 antibody, adaptor antibody, fadd antibody, mort1 antibody, xfadd antibody, Fas associated via death domain antibody, Fas (TNFRSF6)-associated via death domain antibody, Fas associated via death domain S homeolog antibody, Fas (tnfrsf6)-associated via death domain antibody, FADD antibody, Fadd antibody, fadd.S antibody, fadd antibody
    Background
    Fas-associated death domain (FADD, also known as MORT1) is an important apoptosis adapter molecule involved in the Fas-mediated cell death pathway. FADD associates with the intracellular domain of FAS (CD95/APO-1) through their respective C-terminal death domains (DD). The N-terminal region of FADD contains a death effectors domain (DED) which recruits and binds cytosolic proteins such as FLICE/caspase-8. The subsequent activation of FLICE by proteolytic cleavage leads to the activation of the caspase-mediated (ICE-related proteases) apoptotic cascade. Overexpression of FADD induces apoptosis which is inhibited by CrmA, a specific inhibitor of the interleukin-1 β -converting enzyme. FADD has also been shown under certain circumstances to promote cell survival and proliferation.
    Pathways
    Apoptosis, TLR Signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
You are here:
Support