EGFR antibody (Epidermal Growth Factor Receptor) (Extracellular Domain)

Details for Product anti-EGFR Antibody No. ABIN378988
Antigen
  • C-erb
  • CG10079
  • D-EGFR
  • D-Egf
  • DEGFR
  • DER
  • DER flb
  • DER/EGFR
  • DER/faint little ball
  • DER/top
  • DER/torpedo
  • DER1
  • DEgfr
  • Degfr
  • Der
  • DmHD-33
  • Dmel\\CG10079
  • EFG-R
  • EGF-R
  • EGFR
  • EGFr
  • EGfr
  • EK2-6
  • Egf
  • Egf-r
  • EgfR
  • El
  • Elp
  • Elp-1
  • Elp-B1
  • Elp-B1RB1
  • HD-33
  • TOP
  • Torpedo/DER
  • Torpedo/Egfr
  • c-erbB
  • d-egf-r
  • dEGFR
  • dEGFR1
  • dEgfr
  • der
  • egfr
  • flb
  • l(2)05351
  • l(2)09261
  • l(2)57DEFa
  • l(2)57EFa
  • l(2)57Ea
  • mor1
  • top
  • top/DER
  • top/flb
  • torpedo/Egfr
  • torpedo/egfr
  • EGFR12
  • EGFR15
  • egfr1
  • Erbb2
  • ERBB
  • ERBB1
  • HER1
  • PIG61
  • mENA
  • ErbB-1
  • Errp
  • 9030024J15Rik
  • AI552599
  • Erbb
  • Errb1
  • Wa5
  • wa-2
  • wa2
  • epidermal growth factor receptor
  • Epidermal growth factor receptor
  • epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • EGFR
  • Egfr
  • egfra
  • egfr1
  • LOC5564544
Epitope
Extracellular Domain
78
75
69
65
63
62
61
61
58
56
43
41
41
39
35
31
30
24
24
24
23
23
22
21
19
18
17
17
16
15
15
15
15
14
12
12
11
10
10
9
8
8
7
6
6
6
6
6
6
6
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
2164
894
820
31
23
20
18
16
14
6
4
3
2
2
2
2
2
2
1
1
1
1
Host
Mouse
1526
594
23
19
13
5
2
1
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
This EGFR antibody is un-conjugated
101
53
52
43
43
41
41
41
41
41
34
30
16
16
16
16
16
10
8
8
8
8
8
8
8
8
8
8
8
8
8
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunoprecipitation (IP), Western Blotting (WB)
1359
595
562
377
334
273
230
210
86
74
67
56
37
32
24
19
14
11
9
6
6
4
4
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Options
Immunogen BALB/C mice were injected with extracellular domain of human recombinant EGFR protein.
Clone 111-6
Isotype IgG1
Specificity Is specific to 170 kD known as first member (EGF- Receptor) of type I Family of growth factor receptors. Its epitope maps in the extracellular domain of EGFR. Overexpression of EGFR has been reported in tumors of breast, brain, bladder, lung, gastric, head and neck, esophagus, cervix, vulva, ovary and endometrium. EGFR is over expressed in squamous cell carcinoma.
Purification Ig fraction
Plasmids, Primers & others Plasmids, Primers & others EGFR products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name EGFR (EGFR Antibody Abstract)
Background Name/Gene ID: EGFR
Subfamily: EGF Receptor
Family: Protein Kinase

Synonyms: EGFR, EGFf receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1
Gene ID 1956
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
Application Notes Approved: IP (1:50), WB (1:50 - 1:100)
Comment

Target Species of Antibody: Human

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Buffer contains: 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze.
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