MSH2 antibody

Details for Product No. ABIN379092
Target
Reactivity
Human
102
46
27
8
7
6
4
3
3
3
3
2
1
1
1
1
Host
Mouse
79
22
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
5
4
4
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
69
41
32
29
21
19
13
10
8
5
4
3
3
2
1
Options
Immunogen BALB/C mice were injected with recombinant human MSH2 protein.
Clone 25D12
Isotype IgG1, kappa
Specificity Reacts with a 102 kD protein known as MSH2 (Mismatch Repair protein 2). MSH2 protein is involved in the initial recognition of mismatched nucleotides during the post replication mismatch repair process. Loss of MSH2 function leads to the accumulation of replication errors, which in turn may be responsible for the multiple mutations required for multistage carcinogenesis.
Purification Tissue culture supernatant
Target
Background Name/Gene ID: MSH2

Synonyms: MSH2, COCA1, FCC1, HNPCC, HNPCC1, MutS protein homolog 2, HMSH2, LCFS2
Gene ID 4436
Pathways DNA Damage Repair, Production of Molecular Mediator of Immune Response
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Target Species of Antibody: Human

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Buffer contains: 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze.