Thyroperoxidase antibody (Thyroid Peroxidase)

Details for Product anti-TPO Antibody No. ABIN379219
Antigen
  • MSA
  • TDH2A
  • TPX
  • TPO
  • msa
  • tpx
  • xtpo
  • LOC100218312
  • thyroid peroxidase
  • TPO
  • Tpo
  • tpo
  • LOC100547103
Reactivity
Human
120
31
24
1
1
1
1
1
1
Host
Mouse
71
57
9
Clonality (Clone)
Monoclonal ()
Conjugate
This Thyroperoxidase antibody is un-conjugated
14
9
8
5
5
2
2
2
2
2
2
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
80
80
19
14
12
8
7
6
5
3
3
2
1
1
1
1
1
1
1
Options
Immunogen Human Thyroid Peroxidase (hTPO) purified from thyroid microsomes by immunoaffinity chromatography.
Clone MoAb47
Isotype IgG1
Specificity Thyroid Peroxidase (TPO) is a transmembrane protein of 107kD containing a heme prosthetic group and it is present as dimmer on the apical surface of the thyroid follicular cells. TPO is the primary enzyme involved in thyroid hormone synthesis. Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. may be useful aid in the differentiation between the benign and malignant thyroid tumors.
Purification Tissue culture supernatant
Plasmids, Primers & others Plasmids, Primers & others Thyroperoxidase products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name TPO / Thyroid Peroxidase (TPO Antibody Abstract)
Background Name/Gene ID: TPO

Synonyms: TPO, MSA, Thyroid microsomal antigen, Thyroid peroxidase, TDH2A, TPX, Thyroperoxidase
Gene ID 7173
Pathways Thyroid Hormone Synthesis
Application Notes Approved: IHC, IHC-P (1:10 - 1:25)

Usage: High temperature treatment of FFPE tissue sections with 1  mM EDTA buffer,  pH 9.0 must be performed prior to immunostaining.
Comment

Target Species of Antibody: Human

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Tissue culture supernatant, sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze.
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