MGMT antibody (O6-Methylguanine-DNA-Methyltransferase)

Details for Product anti-MGMT Antibody No. ABIN379229
Antigen
  • AGT
  • AI267024
  • Agat
  • O-6-methylguanine-DNA methyltransferase
  • MGMT
  • Mgmt
Reactivity
Human
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45
23
5
5
2
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2
1
1
1
Host
Mouse
138
58
1
Clonality (Clone)
Monoclonal ()
Conjugate
This MGMT antibody is un-conjugated
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6
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3
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2
1
Application
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
168
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30
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22
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9
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Options
Immunogen Recombinant human MGMT protein.

Type of Immunogen: Recombinant protein
Clone MT3-1
Isotype IgG1
Specificity O6-Methylguanine-DNA-Methyltransferase (MGMT) is a 22 kD human DNA repair protein that removes O6-alkylguanine DNA adducts. MGMT acts as a suicide acceptor protein repairing the DNA by accepting alkyl groups and consequently inactivating itself. stains all mantle zone lymphocytes and 50 % of germinal center lymphocytes. Basaloid epithelial cells of tonsil squamous mucosa were also stained positive with this antibody.
Purification Tissue culture supernatant
Plasmids, Primers & others Plasmids, Primers & others MGMT products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name MGMT (MGMT Antibody Abstract)
Background Name/Gene ID: MGMT

Synonyms: MGMT
Gene ID 4255
Pathways DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Target Species of Antibody: Human

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Buffer contains: 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze.
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