PRDM2 antibody (AA 245-573)

Catalog No. ABIN388010

Product Details anti-PRDM2 Antibody

Target: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Binding Specificity: AA 245-573

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRDM2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: Purified recombinant GST fusion protein encoding aa 245-573 of rat PRDM2.

Clone: HS1637

Isotype: IgG

Application Details

Application Notes: IHC-P: 1:100~500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PRDM2

Target: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Alternative Name: PRDM2 (RIZ1) (PRDM2 Products)

Synonyms: MGC114763 antibody, prdm2 antibody, riz antibody, kmt8 antibody, riz1 antibody, riz2 antibody, mtb-zf antibody, humhoxy1 antibody, PRDM2 antibody, HUMHOXY1 antibody, KMT8 antibody, MTB-ZF antibody, RIZ antibody, RIZ1 antibody, RIZ2 antibody, 4833427P12Rik antibody, E330024L24Rik antibody, Gm1033 antibody, Gm19732 antibody, Riz antibody, Riz1 antibody, Znfpr1c1 antibody, PR domain containing 2, with ZNF domain S homeolog antibody, PR domain containing 2, with ZNF domain b antibody, PR domain containing 2, with ZNF domain antibody, PR domain zinc finger protein 2 antibody, PR/SET domain 2 antibody, prdm2.S antibody, prdm2b antibody, prdm2 antibody, LOC100350859 antibody, PRDM2 antibody, Prdm2 antibody

Background: PRDM2 is a 250-kD nuclear protein containing 8 zinc finger motifs. It contains an RB-binding motif that is related to that of the adenovirus E1A oncoprotein, RIZ also shares an antigenic epitope with the C terminus of E1A. It is expressed in human retinoblastoma cells and at low levels in all other human cell lines examined. Using fluorescence in situ hybridization, the PRDM2 gene has been mapped to 1p36. PRDM2 may be a candidate target of 1p36 alterations that commonly occur in neuroendocrine, breast, liver, colon, skin, and lymphoid tumors.

Molecular Weight: 187555

Gene ID: 7799

NCBI Accession: NP_001007258, NP_001129082, NP_036363, NP_056950

UniProt: Q63755