EIF2B3 antibody (C-Term)

Catalog No. ABIN388637

Product Details anti-EIF2B3 Antibody

Target: EIF2B3 (Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))

Binding Specificity: AA 344-376, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2B3 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Pr

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This EIF2B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-376 amino acids from the C-terminal region of human EIF2B3.

Clone: RB8435

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for EIF2B3

Target: EIF2B3 (Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))

Alternative Name: EIF2B3 (EIF2B3 Products)

Synonyms: zgc:56473 antibody, 1190002P15Rik antibody, EIF-2B antibody, EIF2Bgamma antibody, eukaryotic translation initiation factor 2B subunit gamma L homeolog antibody, eukaryotic translation initiation factor 2B, subunit 3 gamma antibody, eukaryotic translation initiation factor 2B subunit gamma antibody, eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa antibody, eukaryotic translation initiation factor 2B, subunit 3 antibody, eif2b3.L antibody, eif2b3 antibody, EIF2B3 antibody, Eif2b3 antibody

Background: EIF2B3 catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Mutations in each of the five subunits of translation initiation factor eIF2B, including subunit 3, can cause leukoencephalopathy with vanishing white matter. EIF2B3 has also been identified as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation.

Molecular Weight: 50240

Gene ID: 8891

NCBI Accession: NP_001160060, NP_001248347, NP_065098

UniProt: Q9NR50