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NMD3 antibody (C-Term)

NMD3 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB9708 unconjugated
Catalog No. ABIN388665
  • Target See all NMD3 Antibodies
    NMD3 (60S Ribosomal Export Protein NMD3 (NMD3))
    Binding Specificity
    • 8
    • 6
    • 1
    • 1
    AA 410-440, C-Term
    Reactivity
    • 19
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 19
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    This NMD3 antibody is un-conjugated
    Application
    • 19
    • 14
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This NMD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-440 amino acids from the C-terminal region of human NMD3.
    Clone
    RB9708
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    NMD3 (60S Ribosomal Export Protein NMD3 (NMD3))
    Alternative Name
    NMD3 (NMD3 Products)
    Synonyms
    RGD1308468 antibody, C87860 antibody, nmd3l antibody, zgc:113103 antibody, NMD3 ribosome export adaptor antibody, NMD3 homolog (S. cerevisiae) antibody, NMD3 ribosome export adaptor L homeolog antibody, Nmd3 antibody, NMD3 antibody, nmd3 antibody, nmd3.L antibody
    Background
    It has been suggested that NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit but is not a ribosomal protein. A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. The NMD3 protein sequence does not contain readily recognizable motifs of known function. However, NMD3 orthologues display an amino-terminal domain containing four repeats of Cx2C, reminiscent of zinc-binding proteins, implicated in nucleic acid binding or protein oligomerization.
    Molecular Weight
    57603
    Gene ID
    51068
    NCBI Accession
    NP_057022
    UniProt
    Q96D46
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