LEO1 antibody (pSer551)

Catalog No. ABIN389947

Product Details anti-LEO1 Antibody

Target: LEO1 (Leo1, Paf1/RNA Polymerase II Complex Component, Homolog (S. Cerevisiae) (LEO1))

Binding Specificity: pSer551

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LEO1 antibody is un-conjugated

Application: Dot Blot (DB)

Predicted Reactivity: Zf, M, Rat, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Leo1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S551 of human Leo1.

Clone: RB15359

Isotype: Ig Fraction

Application Details

Application Notes: DB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for LEO1

Target: LEO1 (Leo1, Paf1/RNA Polymerase II Complex Component, Homolog (S. Cerevisiae) (LEO1))

Alternative Name: LEO1 (LEO1 Products)

Synonyms: LEO1 antibody, RDL antibody, Gm185 antibody, zgc:77374 antibody, LEO1 homolog, Paf1/RNA polymerase II complex component antibody, Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) antibody, RNA polymerase-associated protein LEO1 antibody, LEO1 homolog, Paf1/RNA polymerase II complex component S homeolog antibody, Leo1, Paf1/RNA polymerase II complex component antibody, LEO1 antibody, leo1 antibody, LOC100466503 antibody, leo1.S antibody, Leo1 antibody, LOC415420 antibody, LOC478310 antibody

Background: The PAF1 complex is a multifunctional complex. The PAF1 complex interacts with POLR2A. It may be involved in both initiation and elongation, histone methylation and RNA processing. Overexpression of LEO1 induces cell growth arrest and premature senescence of fibroblasts.

Molecular Weight: 75404

Gene ID: 123169

NCBI Accession: NP_620147

UniProt: Q8WVC0

Pathways: Stem Cell Maintenance