Kallikrein 5 antibody (AA 144-174)

Catalog No. ABIN390305

Product Details anti-Kallikrein 5 Antibody

Target: Kallikrein 5 (KLK5)

Binding Specificity: AA 144-174

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 5 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Kallikrein 5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-174 amino acids from the Central region of human Kallikrein 5.

Clone: RB6112

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-Kallikrein 5 antibody (ABIN390305)

Jennemann, Rabionet, Gorgas, Epstein, Dalpke, Rothermel, Bayerle, van der Hoeven, Imgrund, Kirsch, Nickel, Willecke, Riezman, Gröne, Sandhoff: "Loss of ceramide synthase 3 causes lethal skin barrier disruption." in: Human molecular genetics, Vol. 21, Issue 3, pp. 586-608, (2012) (PubMed).

Target Details for Kallikrein 5

Target: Kallikrein 5 (KLK5)

Abstract: KLK5 Products

Synonyms: KLK-L2 antibody, KLKL2 antibody, SCTE antibody, 1110030O19Rik antibody, KAL antibody, KALA antibody, Klk1 antibody, Klk5 antibody, RATKALA antibody, kallikrein related peptidase 5 antibody, kallikrein related-peptidase 5 antibody, kallikrein 5-like antibody, KLK5 antibody, Klk5 antibody, Klk5l antibody

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK5 expression is up-regulated by estrogens and progestins. The protein is secreted and may be involved in desquamation in the epidermis.

Molecular Weight: 32020

Gene ID: 25818

NCBI Accession: NP_001070959, NP_001070960, NP_036559

UniProt: Q9Y337

Pathways: Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling