PCM1 antibody (AA 632-661)

Catalog No. ABIN391696

Product Details anti-PCM1 Antibody

Target: PCM1 (Pericentriolar Material 1 (PCM1))

Binding Specificity: AA 632-661

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCM1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PCM-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 632-661 amino acids from the Central region of human PCM-1.

Clone: RB18191

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-PCM1 antibody (ABIN391696)

Fang, Zhang, Yin, Zheng, Bi, Yuan: "Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion." in: Journal of cell science, Vol. 127, Issue Pt 8, pp. 1631-9, (2014) (PubMed).

Target Details for PCM1

Target: PCM1 (Pericentriolar Material 1 (PCM1))

Alternative Name: PCM-1 (PCM1 Products)

Background: PCM-1 is required for centrosome assembly and function. This protein is essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2. The protein is required to anchor microtubules to the centrosome.

Molecular Weight: 228544

Gene ID: 5108

NCBI Accession: NP_006188

UniProt: Q15154

Pathways: Stem Cell Maintenance, M Phase, Maintenance of Protein Location