PTPN7 antibody (AA 22-51)

Catalog No. ABIN391869

Product Details anti-PTPN7 Antibody

Target: PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

Binding Specificity: AA 22-51

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PTPN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from human PTPN7.

Clone: RB11327

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PTPN7

Target: PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

Alternative Name: PTPN7 (PTPN7 Products)

Synonyms: BPTP-4 antibody, HEPTP antibody, LC-PTP antibody, LPTP antibody, PTPNI antibody, C920001D21Rik antibody, Heptp antibody, Lcptp antibody, protein tyrosine phosphatase, non-receptor type 7 antibody, PTPN7 antibody, Ptpn7 antibody

Background: PTPN7 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN7 is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP has been shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which is thought to function through dephosphorylating the molecules related to MAP kinase pathway.

Molecular Weight: 40529

Gene ID: 5778

NCBI Accession: NP_542155

UniProt: P35236