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PHLPP2 antibody (N-Term)

PHLPP2 Reactivity: Human WB Host: Rabbit Polyclonal RB15006 unconjugated
Catalog No. ABIN392229
  • Target See all PHLPP2 Antibodies
    PHLPP2 (PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
    Binding Specificity
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 4-31, N-Term
    Reactivity
    • 16
    • 5
    • 2
    • 1
    • 1
    Human
    Host
    • 15
    • 1
    Rabbit
    Clonality
    • 16
    Polyclonal
    Conjugate
    • 16
    This PHLPP2 antibody is un-conjugated
    Application
    • 15
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Predicted Reactivity
    M
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PHLPP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-31 amino acids from the N-terminal region of human PHLPP2.
    Clone
    RB15006
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PHLPP2 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    PHLPP2 (PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
    Alternative Name
    PHLPP2 (PHLPP2 Products)
    Synonyms
    PHLPPL antibody, phlppl antibody, AI481772 antibody, C130044A18Rik antibody, Phlppl antibody, RGD1562857 antibody, PH domain and leucine rich repeat protein phosphatase 2 antibody, PH domain and leucine rich repeat protein phosphatase 2 S homeolog antibody, PHLPP2 antibody, phlpp2.S antibody, phlpp2 antibody, Phlpp2 antibody
    Background
    PHLPP2 is a protein phosphatase that specifically mediates dephosphorylation of 'Ser-473' of AKT1. This protein regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decrease cell proliferation. It also controls the phosphorylation of AKT3.
    Molecular Weight
    146751
    Gene ID
    23035
    NCBI Accession
    NP_055835
    UniProt
    Q6ZVD8
    Pathways
    PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway
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