PPP3CC antibody (N-Term)

Catalog No. ABIN392895

Product Details anti-PPP3CC Antibody

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Binding Specificity: AA 18-47, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP3CC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PPP3CC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-47 amino acids from the N-terminal region of human PPP3CC.

Clone: RB6008

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PPP3CC

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Alternative Name: PPP3CC (PPP3CC Products)

Synonyms: CALNA3 antibody, CNA3 antibody, PP2Bgamma antibody, Calnc antibody, ppp3cc antibody, sb:cb767 antibody, si:dkey-21k4.5 antibody, calna3 antibody, cna3 antibody, pp2bgamma antibody, im:7163784 antibody, zgc:158685 antibody, protein phosphatase 3 catalytic subunit gamma antibody, protein phosphatase 3, catalytic subunit, gamma isoform antibody, protein phosphatase 3, catalytic subunit, gamma isozyme, a antibody, protein phosphatase 3, catalytic subunit, gamma isozyme antibody, protein phosphatase 3, catalytic subunit, gamma isozyme L homeolog antibody, protein phosphatase 3, catalytic subunit, gamma isozyme, b antibody, PPP3CC antibody, Ppp3cc antibody, ppp3cca antibody, ppp3cc antibody, ppp3cc.L antibody, ppp3ccb antibody

Background: Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95 % amino acid identity).

Molecular Weight: 58129

Gene ID: 5533

NCBI Accession: NP_001230903, NP_001230904, NP_005596

UniProt: P48454

Pathways: RTK Signaling, WNT Signaling, VEGF Signaling, BCR Signaling