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Antigen Type: Recombinant Protein
Target/Specificity: SSH2 (NP_203747, 20 a.a. ~ 117 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Other Names: Protein phosphatase Slingshot homolog 2, SSH-like protein 2, SSH-2L, hSSH-2L, SSH2, KIAA1725, SSH2L
Gene Description: slingshot homolog 2 (Drosophila)
Gene Summary: The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1, MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM