BAX antibody (BCL2-Associated X Protein) (AA 3-16)

Details for Product anti-BAX Antibody No. ABIN4283108, Supplier: Log in to see
Antigen
  • BAX-ALPHA
  • bax-A
  • xBax
  • xlbax
  • BAX
  • bax
  • fj16e01
  • wu:fc50b10
  • wu:fj16e01
  • BCL2L4
  • BCL2 associated X, apoptosis regulator
  • BCL2-associated X protein L homeolog
  • BCL2-associated X protein
  • bcl2-associated X protein, a
  • BAX
  • bax.L
  • bax
  • baxa
  • Bax
Alternatives
anti-Human BAX antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 3-16
89
77
31
22
21
19
15
13
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12
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10
9
9
9
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5
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4
4
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3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Primate
557
233
214
128
44
31
28
23
21
11
7
7
6
5
3
3
3
2
2
2
1
1
1
1
1
Host
Mouse
348
243
4
2
Clonality (Clone)
Monoclonal ()
Conjugate
This BAX antibody is un-conjugated
19
15
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12
11
9
8
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5
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3
3
3
3
3
3
3
3
3
3
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3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
455
230
194
168
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113
47
42
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32
26
13
5
5
2
2
1
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein
Clone SPM336
Isotype IgG1
Specificity Recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
No Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Protein G purified
Plasmids, Primers & others Plasmids, Primers & others BAX products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Bax (BAX Antibody Abstract)
Background Gene Symbol: BAX
Molecular Weight Theoretical MW: 21 kDa
Gene ID 581
UniProt Q07812
Pathways p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded protein response
Application Notes Western Blot 0.5-1 μg/mL, Flow Cytometry 0.5-1 μg/million cells, Immunocytochemistry/Immunofluorescence 1-2 μg/mL, Immunoprecipitation 0.5-1 μg/500 μg protein lysate, Immunohistochemistry-Paraffin 0.5-1.0 μg/mL, Immunohistochemistry-Frozen 0.5-1.0 μg/mLELISA (For coating, order NBP2-34763 (BSA free version of NBP2-32809))
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % BSA.
Buffer contains: 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C.
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