HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian)) (pTyr877)

Details for Product anti-ERBB2 Antibody No. ABIN4309120, Supplier: Log in to see
Antigen
  • CD340
  • HER-2
  • HER-2/neu
  • HER2
  • MLN 19
  • NEU
  • NGL
  • TKR1
  • Erbb-2
  • Neu
  • c-erbB2
  • c-neu
  • mKIAA3023
  • wu:fv70f10
  • zgc:63601
  • erb2
  • erb-b2 receptor tyrosine kinase 2
  • ERBB2
  • Erbb2
  • erbb2
Alternatives
anti-Human HER2 antibody for Western Blotting
Epitope
pTyr877
128
86
70
68
59
48
48
35
30
30
25
22
21
16
15
15
13
13
12
12
11
11
11
11
11
11
11
11
11
11
11
11
10
8
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5
5
4
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
1302
399
296
28
21
8
4
4
4
4
3
3
3
2
1
1
1
Host
Rabbit
786
587
29
14
11
3
3
Clonality
Polyclonal
Conjugate
This HER2 antibody is un-conjugated
59
45
44
42
41
27
20
20
13
13
13
13
11
11
8
8
8
8
8
7
7
7
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6
6
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6
6
6
6
6
3
2
2
1
Application
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
668
466
429
397
341
201
197
102
102
100
87
47
24
21
18
11
6
4
3
3
2
2
1
1
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Synthetic phosphopeptide derived from human ErbB2/HER2 around the phosphorylation site of Tyrosine 877.
Specificity P-HER2 (Y877) detects endogenous levels of p-HER2 (Y877) protein.
Purification Immunogen affinity purified
Plasmids, Primers & others Plasmids, Primers & others HER2 products on genomics-online (e.g. as negative or positive controls)
Alternative Name ErbB2/Her2 (ERBB2 Antibody Abstract)
Background Gene Symbol: ERBB2
Molecular Weight Theoretical MW: 138 kDa
Gene ID 2064
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
Application Notes Western Blot 1:500-1:1000, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:500-1:200, Immunohistochemistry-Paraffin 1:50-1:200Western blot (WB) analysis of p-HER2 (Y877) pAb in extracts from MDA-MB-231 cells treated with EGFImmunohistochemistry (IHC) analyzes of p-HER2 (Y877) pAb in paraffin-embedded human breast carcinoma tissue. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS ( pH 7.2)
Buffer contains: 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Supplier Images
Immunohistochemistry (IHC) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr877) antibody (ABIN4309120) Immunohistochemistry: HER2 Phosphospecific Antibody [ABIN43091209] - Immunohistochemi...
Western Blotting (WB) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr877) antibody (ABIN4309120) Western Blot: HER2 Phosphospecific Antibody [ABIN43091209] - Western blot (WB) analys...
Product cited in: Scrima, De Marco, De Vita, Fabiani, Franco, Pirozzi, Rocco, Malanga, Viglietto: "The nonreceptor-type tyrosine phosphatase PTPN13 is a tumor suppressor gene in non-small cell lung cancer." in: The American journal of pathology, Vol. 180, Issue 3, pp. 1202-14, 2012 (PubMed).

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