CD74 antibody (HLA-DR-gamma) (N-Term)

Details for Product anti-CD74 Antibody No. ABIN443052
Antigen
  • DHLAG
  • HLADG
  • II
  • Ia-GAMMA
  • CLIP
  • Ii
  • INVG34
  • Iclp-1
  • iclp1
  • wu:fb11f09
  • wu:fb12a01
  • wu:fb13d06
  • wu:fk94e07
  • CD74 molecule
  • CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  • CD74 molecule, major histocompatibility complex, class II invariant chain a
  • CD74
  • Cd74
  • cd74a
Epitope
N-Term
42
26
16
15
7
5
4
4
4
3
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
521
121
31
27
Host
Rabbit
447
103
4
2
Clonality
Polyclonal
Conjugate
This CD74 antibody is un-conjugated
34
32
25
20
19
16
14
9
9
9
9
9
9
9
9
9
8
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
343
330
234
134
98
95
63
61
58
54
16
13
10
2
2
2
2
2
1
1
Options
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CD74. The exact sequence is proprietary.
Isotype IgG
Purification Immunogen affinity purified
Plasmids, Primers & others Plasmids, Primers & others CD74 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CD74 (CD74 Antibody Abstract)
Background Gene Symbol: CD74
Molecular Weight Theoretical MW: 34 kDa
Gene ID 972
UniProt P04233
Pathways Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
Application Notes Western Blot 1:1000-1:10000, Immunohistochemistry 1:100-1:1000, Immunohistochemistry-Paraffin 1:100-1:1000The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.88 mg/mL
Buffer PBS ( pH 7.0) and 20 % Glycerol
Buffer contains: 0.025 % Proclin 300
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -80 °C,-20 °C
Storage Comment Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-HLA-DR-gamma (CD74) (N-Term) antibody (ABIN443052) Western Blot: CD74 Antibody [NBP1-33109] - Sample (30 ug of whole cell lysate) A: Raji.
Image no. 2 for anti-HLA-DR-gamma (CD74) (N-Term) antibody (ABIN443052) Immunohistochemistry-Paraffin: CD74 Antibody [NBP1-33109] - Paraffin-embedded SW480 x...
Image no. 3 for anti-HLA-DR-gamma (CD74) (N-Term) antibody (ABIN443052) Immunohistochemistry-Paraffin: CD74 Antibody [NBP1-33109] - Human lung carcinoma dilu...
Image no. 4 for anti-HLA-DR-gamma (CD74) (N-Term) antibody (ABIN443052) Western Blot: CD74 Antibody [NBP1-33109] - A. 30 ug GL261 whole cell lysate/extract 1...
Image no. 5 for anti-HLA-DR-gamma (CD74) (N-Term) antibody (ABIN443052) Western Blot: CD74 Antibody [NBP1-33109] - Whole cell extracts (30ug) was separated b...
Image no. 6 for anti-HLA-DR-gamma (CD74) (N-Term) antibody (ABIN443052) Western Blot: CD74 Antibody [NBP1-33109] - A. 30 ug Rat2 whole cell lysate/extract 12...
Product cited in: Ishihara, Kariya, Okano, Zhao, Maeda, Nishizaki: "Expression of macrophage migration inhibitory factor and CD74 in the inner ear and middle ear in lipopolysaccharide-induced otitis media." in: Acta oto-laryngologica, Vol. 136, Issue 10, pp. 1011-6, 2016 (PubMed). Further details: Immunohistochemistry

Uhlenbrock, van Andel, Andresen, Skov: "A conserved WW domain-like motif regulates invariant chain-dependent cell-surface transport of the NKG2D ligand ULBP2." in: Molecular immunology, Vol. 66, Issue 2, pp. 418-27, 2015 (PubMed). (Sample species: Human). Further details: Western Blotting

Uhlenbrock, Hagemann-Jensen, Kehlet, Andresen, Pastorekova, Skov: "The NKG2D ligand ULBP2 is specifically regulated through an invariant chain-dependent endosomal pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 4, pp. 1654-65, 2014 (PubMed). (Sample species: Human). Further details: Western Blotting

Did you look for something else?