CD74 antibody (HLA-DR-gamma) (N-Term)

Details for Product anti-CD74 Antibody No. ABIN443052
Target
Binding Specificity
N-Term
42
20
15
12
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse, Rat
297
85
27
22
Host
Rabbit
242
77
2
2
Clonality
Polyclonal
Conjugate
This CD74 antibody is un-conjugated
22
18
12
10
9
7
5
5
5
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
183
166
159
77
56
48
46
40
38
25
13
9
4
2
2
2
2
1
1
1
Options
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CD74. The exact sequence is proprietary.
Isotype IgG
Purification Immunogen affinity purified
Target
Alternative Name CD74 (CD74 Antibody Abstract)
Background Gene Symbol: CD74
Molecular Weight Theoretical MW: 34 kDa
Gene ID 972
UniProt P04233
Pathways Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
Application Notes Western Blot 1:1000-1:10000, Immunohistochemistry 1:100-1:1000, Immunohistochemistry-Paraffin 1:100-1:1000The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.88 mg/mL
Buffer PBS ( pH 7.0) and 20 % Glycerol
Buffer contains: 0.025 % Proclin 300
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -80 °C,-20 °C
Storage Comment Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Images
Image no. 1 for anti-HLA-DR-gamma (CD74) (N-Term) antibody (ABIN443052) Western Blot: CD74 Antibody [NBP1-33109] - Sample (30 ug of whole cell lysate) A: Raji.
Image no. 2 for anti-HLA-DR-gamma (CD74) (N-Term) antibody (ABIN443052) Immunohistochemistry-Paraffin: CD74 Antibody [NBP1-33109] - Paraffin-embedded SW480 x...
Image no. 3 for anti-HLA-DR-gamma (CD74) (N-Term) antibody (ABIN443052) Immunohistochemistry-Paraffin: CD74 Antibody [NBP1-33109] - Human lung carcinoma dilu...
Image no. 4 for anti-HLA-DR-gamma (CD74) (N-Term) antibody (ABIN443052) Western Blot: CD74 Antibody [NBP1-33109] - A. 30 ug GL261 whole cell lysate/extract 1...
Image no. 5 for anti-HLA-DR-gamma (CD74) (N-Term) antibody (ABIN443052) Western Blot: CD74 Antibody [NBP1-33109] - Whole cell extracts (30ug) was separated b...
Image no. 6 for anti-HLA-DR-gamma (CD74) (N-Term) antibody (ABIN443052) Western Blot: CD74 Antibody [NBP1-33109] - A. 30 ug Rat2 whole cell lysate/extract 12...
Product cited in: Ishihara, Kariya, Okano, Zhao, Maeda, Nishizaki: "Expression of macrophage migration inhibitory factor and CD74 in the inner ear and middle ear in lipopolysaccharide-induced otitis media." in: Acta oto-laryngologica, Vol. 136, Issue 10, pp. 1011-6, 2016 (PubMed). Further details: Immunohistochemistry

Uhlenbrock, van Andel, Andresen, Skov: "A conserved WW domain-like motif regulates invariant chain-dependent cell-surface transport of the NKG2D ligand ULBP2." in: Molecular immunology, Vol. 66, Issue 2, pp. 418-27, 2015 (PubMed). (Sample species: Human). Further details: Western Blotting

Uhlenbrock, Hagemann-Jensen, Kehlet, Andresen, Pastorekova, Skov: "The NKG2D ligand ULBP2 is specifically regulated through an invariant chain-dependent endosomal pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 4, pp. 1654-65, 2014 (PubMed). (Sample species: Human). Further details: Western Blotting