GTP Cyclohydrolase 1 (GCH1) antibody

Details for Product No. ABIN451682, Supplier: Log in to see
Antigen
  • DYT14
  • DYT5
  • DYT5a
  • GCH
  • GTP-CH-1
  • GTPCH1
  • HPABH4B
  • GTP-CH
  • GTPCH
  • Gch
  • MGC89622
  • gch1a
  • wu:fc16b10
  • zgc:195269
  • GTP cyclohydrolase 1
  • GTP cyclohydrolase 1-like
  • GCH1
  • Gch1
  • gch1
  • Weevi_1190
  • Halhy_0838
  • Sinme_1220
  • Sphch_1077
  • LOC100136794
Reactivity
Human
83
33
32
5
5
4
3
3
2
2
2
2
2
1
1
1
Host
Goat
57
16
12
Clonality
Polyclonal
Conjugate
Un-conjugated
7
6
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
69
50
28
13
8
8
7
1
1
Options
Supplier
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Immunogen Peptide with sequence C-GKVHIGYLPNKQ corresponding to internal region according to NP_001019195.1, NP_001019241.1, NP_001019242.1 .
Specificity This antibody is expected to recognize all four isoforms (NP_000152.1 , NP_001019195.1 , NP_001019241.1 , NP_001019242.1)
Purification Immunogen affinity purified
Antigen
Alternative Name GCH1 (GCH1 Antibody Abstract)
Background Gene Symbol: GCH1
Gene ID 2643
NCBI Accession NP_000152
Application Notes Western Blot 0.5 - 1.5 μg/mL, Peptide ELISA Detection limit 1:16000WB: Approx. 37 kDa band observed in human tonsil, lymph node and thymus lysates. An anonymous customer has reported identical results in HUVEC lysates with antibodies raised against different parts of the same protein (calculated MW of 27.9 kDa band according to NP_000152.1).
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer 0.5 mg/mL Tris ( pH 7.3) and 0.5 % BSA
Buffer contains: 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-GTP Cyclohydrolase 1 (GCH1) antibody (ABIN451682) anti-GTP Cyclohydrolase 1 (GCH1) antibody
Western Blotting (WB) image for anti-GTP Cyclohydrolase 1 (GCH1) antibody (ABIN451682) Western Blot: GCH1 Antibody [NBP1-20923] - (0.5ug/ml) staining of Human Tonsil lysate...
Product cited in: Tegeder, Costigan, Griffin, Abele, Belfer, Schmidt, Ehnert, Nejim, Marian, Scholz, Wu, Allchorne, Diatchenko, Binshtok, Goldman, Adolph, Sama, Atlas, Carlezon, Parsegian, Lötsch, Fillingim, Maixner et al.: "GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence. ..." in: Nature medicine, Vol. 12, Issue 11, pp. 1269-77, 2006 (PubMed).

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