BAX antibody (BCL2-Associated X Protein) (N-Term)

Details for Product anti-BAX Antibody No. ABIN451743, Supplier: Log in to see
Antigen
  • BAX-ALPHA
  • bax-A
  • xBax
  • xlbax
  • BAX
  • bax
  • fj16e01
  • wu:fc50b10
  • wu:fj16e01
  • BCL2L4
  • BCL2 associated X, apoptosis regulator
  • BCL2-associated X protein L homeolog
  • BCL2-associated X protein
  • bcl2-associated X protein, a
  • BAX
  • bax.L
  • bax
  • baxa
  • Bax
Alternatives
anti-Human BAX antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
N-Term
98
60
31
20
20
19
15
13
12
11
10
10
10
10
8
8
5
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Human, Monkey, Mouse (Murine), Rat (Rattus)
489
216
197
83
41
28
26
24
22
9
6
5
5
3
3
2
1
1
1
1
Host
Mouse
322
197
4
Clonality (Clone)
Monoclonal ()
Conjugate
This BAX antibody is un-conjugated
17
15
13
11
10
8
7
6
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
Application
ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
383
212
143
134
118
116
101
47
40
37
13
9
5
5
4
2
1
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen KLH-conjugated peptide corresponding to amino acids 12-24 located near the N-terminus common to human, mouse and rat Bax.
Clone 6A7
Isotype IgG1 kappa
Specificity The monoclonal antibody 6A7 reacts with human, mouse and rat Bax but does not bind the soluble cytosolic form of Bax, however, treatment of cells with non-ionic detergents exposes the epitope and allows binding of 6A7 to monomeric forms of Bax but not Bax complexed with either Bcl-2 or Bcl-xL.
Purification Protein A or G purified
Alternative Name Bax (BAX Antibody Abstract)
Background Gene Symbol: BAX
Gene ID 581
UniProt Q07812
Pathways p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded protein response
Application Notes Western Blot < = 1 μg/mL, Flow Cytometry 1:10-1:1000, ELISA 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.1 mg/mL
Buffer Borate buffered saline, pH 8.2
Buffer contains: No Preservative
Preservative Without preservative
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 4°C. Do not freeze.
Supplier Images
Western Blotting (WB) image for anti-BCL2-Associated X Protein (BAX) (N-Term) antibody (ABIN451743) Western Blot: Bax Antibody (6A7) [NBP1-28566] - Total cell lysates from NIH/3T3 cells...
Immunohistochemistry (Frozen Sections) (IHC (fro)) image for anti-BCL2-Associated X Protein (BAX) (N-Term) antibody (ABIN451743) Immunohistochemistry-Frozen: Bax Antibody (6A7) [NBP1-28566] - Mouse retina with no p...
Western Blotting (WB) image for anti-BCL2-Associated X Protein (BAX) (N-Term) antibody (ABIN451743) Western Blot: Bax Antibody (6A7) [NBP1-28566] - Analysis of lysates from human metast...
Product cited in: Barreto-Vianna, Aguila, Mandarim-de-Lacerda: "Effects of liraglutide in hypothalamic arcuate nucleus of obese mice." in: Obesity (Silver Spring, Md.), Vol. 24, Issue 3, pp. 626-33, 2016 (PubMed). Further details: Western Blotting

Shi, Xu, Doycheva, Tang, Yan, Zhang: "Sestrin2, as a negative feedback regulator of mTOR, provides neuroprotection by activation AMPK phosphorylation in neonatal hypoxic-ischemic encephalopathy in rat pups." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2016 (PubMed).

Xie, Enkhjargal, Wu, Zhou, Sun, Hu, Gospodarev, Tang, You, Zhang: "Exendin-4 attenuates neuronal death via GLP-1R/PI3K/Akt pathway in early brain injury after subarachnoid hemorrhage in rats." in: Neuropharmacology, Vol. 128, pp. 142-151, 1970 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

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