NDUFS4 antibody (C-Term)

Catalog No. ABIN453217

Product Details anti-NDUFS4 Antibody

Target: NDUFS4 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 4, 18kDa (NADH-Coenzyme Q Reductase) (NDUFS4))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFS4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to NDUFS4.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human NDUFS4

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry on paraffin sections: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NDUFS4

Target: NDUFS4 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 4, 18kDa (NADH-Coenzyme Q Reductase) (NDUFS4))

Alternative Name: NDUFS4 (NDUFS4 Products)

Synonyms: 6720411N02Rik antibody, C1-18k antibody, Aqdq antibody, AQDQ antibody, CI-18 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 4 antibody, NADH:ubiquinone oxidoreductase subunit S4 antibody, Ndufs4 antibody, NDUFS4 antibody

Background: NDUFS4 is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase(Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane.Synonyms: CI-18 kDa, CI-AQDQ, Complex I-18 kDa, Complex I-AQDQ, NADH dehydrogenase [ubiquinone] iron-sulfur protein 4 mitochondrial, NADH-ubiquinone oxidoreductase 18 kDa subunit

Gene ID: 4724

NCBI Accession: NP_002486

UniProt: O43181