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TRKA antibody (Tyr791)

NTRK1 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN453859
  • Target See all TRKA (NTRK1) Antibodies
    TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
    Binding Specificity
    • 36
    • 26
    • 25
    • 19
    • 16
    • 15
    • 15
    • 10
    • 10
    • 8
    • 8
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Tyr791
    Reactivity
    • 238
    • 151
    • 144
    • 15
    • 4
    • 4
    • 1
    • 1
    Human
    Host
    • 247
    • 15
    • 3
    • 2
    Rabbit
    Clonality
    • 239
    • 27
    • 1
    Polyclonal
    Conjugate
    • 101
    • 18
    • 15
    • 13
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRKA antibody is un-conjugated
    Application
    • 184
    • 99
    • 79
    • 78
    • 51
    • 38
    • 30
    • 20
    • 19
    • 14
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to TrkA pTyr791.
    Purification
    Affinity chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide selected from the Y791 region of human TrkA
    Top Product
    Discover our top product NTRK1 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
    Alternative Name
    TrkA (NTRK1 Products)
    Synonyms
    MTC antibody, TRK antibody, TRK1 antibody, TRKA antibody, Trk-A antibody, p140-TrkA antibody, CDHF12 antibody, CDHR16 antibody, HSCR1 antibody, MEN2A antibody, MEN2B antibody, MTC1 antibody, PTC antibody, RET-ELE1 antibody, RET51 antibody, Trk antibody, C80751 antibody, Tkr antibody, TrkA antibody, trk antibody, trka antibody, CTRKA antibody, trkA antibody, neurotrophic receptor tyrosine kinase 1 antibody, ret proto-oncogene antibody, neurotrophic tyrosine kinase, receptor, type 1 antibody, NTRK1 antibody, RET antibody, Ntrk1 antibody, ntrk1 antibody
    Background
    TRKA (also known as NTRK1)is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.Synonyms: High affinity nerve growth factor receptor, NTRK1, Neurotrophic tyrosine kinase receptor type 1, TRK, TRK1-transforming tyrosine kinase protein, Trk-A, p140-TrkA
    Gene ID
    4914
    NCBI Accession
    NP_001007793
    UniProt
    P04629
    Pathways
    RTK Signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process
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