LNX1 antibody
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- Target See all LNX1 Antibodies
- LNX1 (Ligand of Numb-Protein X 1 (LNX1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LNX1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody detects LNX1, expressed in heart, placenta, kidney, pancreas and brain.
- Purification
- Affinty chromatography
- Immunogen
- Synthetic peptide derived from the human LNX1 protein
- Top Product
- Discover our top product LNX1 Primary Antibody
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anti-Ligand of Numb-Protein X 1 (LNX1) (AA 19-118) antibody
LNX1 Reactivity: Human ELISA, WB Host: Mouse Monoclonal 4E3 unconjugated
anti-Ligand of Numb-Protein X 1 (LNX1) (AA 133-259) antibodyLNX1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Ligand of Numb-Protein X 1 (LNX1) (AA 19-118) antibodyLNX1 Reactivity: Human ELISA, WB Host: Mouse Polyclonal unconjugated
anti-Ligand of Numb-Protein X 1 (LNX1) (AA 431-480) antibodyLNX1 Reactivity: Human, Mouse, Rat, Pig, Rabbit, Cow, Dog, Horse, Bat, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Ligand of Numb-Protein X 1 (LNX1) (AA 1-632) antibodyLNX1 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
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Western blot (1: 400 starting dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- Phosphate buffered saline with 0.08 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- Target
- LNX1 (Ligand of Numb-Protein X 1 (LNX1))
- Alternative Name
- LNX1 (LNX1 Products)
- Synonyms
- LNX1 antibody, fj78f06 antibody, lnx antibody, si:dkey-12h2.1 antibody, wu:fj78f06 antibody, zgc:152906 antibody, Lnx antibody, LNX antibody, MPDZ antibody, PDZRN2 antibody, ligand of numb-protein X 1 antibody, LNX1 antibody, lnx1 antibody, Lnx1 antibody
- Background
- LNX1 is an E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.Synonyms: E3 ubiquitin-protein ligase LNX, LNX, LNX-1, Ligand of Numb-protein X 1, Numb-binding protein 1
- Gene ID
- 84708
- NCBI Accession
- NP_001119800
- UniProt
- Q8TBB1
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