Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

NAE1 antibody (C-Term)

NAE1 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN359509
  • Target See all NAE1 Antibodies
    NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
    Binding Specificity
    • 15
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 56
    • 25
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 63
    • 8
    Rabbit
    Clonality
    • 65
    • 6
    Polyclonal
    Conjugate
    • 30
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NAE1 antibody is un-conjugated
    Application
    • 64
    • 35
    • 29
    • 13
    • 13
    • 9
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects NAE1 (APPBP1) at C-term.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human APPBP1.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NAE1 Primary Antibody
  • Application Notes
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry on paraffin sections 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
    Alternative Name
    APPBP1 (NAE1 Products)
    Synonyms
    APPBP1 antibody, CG7828 antibody, Dmel\\CG7828 antibody, anon-WO0140519.225 antibody, dAPP-BP1 antibody, dAPPBP1 antibody, A-116A10.1 antibody, ula-1 antibody, Appbp1 antibody, 59kDa antibody, appbp1 antibody, zgc:66148 antibody, beta-Amyloid precursor protein binding protein 1 antibody, NEDD8 activating enzyme E1 subunit 1 antibody, NEDD8 activating enzyme E1 subunit 1 S homeolog antibody, nedd8 activating enzyme E1 subunit 1 antibody, NEDD8-activating enzyme E1 regulatory subunit antibody, APP-BP1 antibody, NAE1 antibody, Nae1 antibody, nae1.S antibody, nae1 antibody, ula-1 antibody
    Background
    APPBP1 binds to the beta-amyloid precursor protein, a cell surface protein with signal-transducing properties thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPB1 is required for cell cycle progression through the S/M checkpoint.Synonyms: Amyloid beta precursor protein-binding protein 1, Amyloid protein-binding protein 1, HPP1, NAE1
    Molecular Weight
    60252 Da
    Gene ID
    8883, 9606
    UniProt
    Q13564
You are here:
Support