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TRPM8 antibody (Middle Region)

TRPM8 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN360716
  • Target See all TRPM8 Antibodies
    TRPM8 (Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8))
    Binding Specificity
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 49
    • 12
    • 8
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 56
    • 1
    Rabbit
    Clonality
    • 54
    • 3
    Polyclonal
    Conjugate
    • 42
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRPM8 antibody is un-conjugated
    Application
    • 33
    • 26
    • 21
    • 15
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to TRPM8.
    Purification
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide at the Center(R536) of human TRPM8.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TRPM8 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Yee, Li, Kazi, Yang, Berg, Yee: "Aberrantly Over-Expressed TRPM8 Channels in Pancreatic Adenocarcinoma: Correlation with Tumor Size/Stage and Requirement for Cancer Cells Invasion." in: Cells, Vol. 3, Issue 2, pp. 500-16, (2014) (PubMed).

  • Target
    TRPM8 (Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8))
    Alternative Name
    TRPM8 (TRPM8 Products)
    Synonyms
    TRPM8 antibody, trpp8 antibody, ltrpc6 antibody, trpm8b antibody, LTRPC6 antibody, TRPP8 antibody, CMR1 antibody, LTrpC-6 antibody, Trp-p8 antibody, transient receptor potential cation channel subfamily M member 8 antibody, transient receptor potential cation channel subfamily M member 8b L homeolog antibody, transient receptor potential cation channel, subfamily M, member 8 antibody, TRPM8 antibody, trpm8b.L antibody, Trpm8 antibody
    Background
    TRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. It is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH and involved in menthol sensation. It is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium.Synonyms: LTRPC6, Long transient receptor potential channel 6, TRPP8, Transient receptor potential cation channel subfamily M member 8, Transient receptor potential-p8, Trp-p8
    Gene ID
    79054, 9606
    UniProt
    Q7Z2W7
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