RPS6KA3 antibody (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3) (AA 604-617)

Details for Product anti-RPS6KA3 Antibody No. ABIN462362, Supplier: Log in to see
Antigen
  • CLS
  • HU-3
  • ISPK-1
  • MAPKAPK1B
  • MRX19
  • RSK
  • RSK2
  • S6K-alpha3
  • p90-RSK2
  • pp90RSK2
  • MPK-9
  • Rsk2
  • RGD1563860
  • ribosomal protein S6 kinase A3
  • ribosomal protein S6 kinase polypeptide 3
  • RPS6KA3
  • Rps6ka3
Alternatives
anti-Human RPS6KA3 antibody for Western Blotting
Epitope
AA 604-617
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Reactivity
Bat, Chicken, Cow (Bovine), Dog (Canine), Hamster, Horse (Equine), Human, Monkey, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
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Host
Rabbit
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Clonality
Polyclonal
Conjugate
This RPS6KA3 antibody is un-conjugated
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Application
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
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Options
Supplier
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Supplier Product No.
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Brand IHC-plus™
Immunogen A 14 residue synthetic peptide (C)NRNQSPVLEPVGRS based on the mouse RSK2 S6 kinase (amino acids 604-617) with the cysteine (C) residue added and the peptide coupled to KLH. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Bat, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus (100%).

Type of Immunogen: Synthetic peptide - KLH conjugated
Specificity Detects an ~90 kD protein, corresponding to the apparent molecular mass of RSK2 on SDS-PAGE immunoblots, in samples from mouse and rat origins.
Predicted Reactivity Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Bat, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus (100%).
Purification Protein A purified
Alternative Name RPS6KA3 / RSK2 (RPS6KA3 Antibody Abstract)
Background Name/Gene ID: RPS6KA3
Subfamily: RSK
Family: Protein Kinase

Synonyms: RPS6KA3, Coffin-Lowry syndrome, HU-2, ISPK1, MAPKAP kinase 1B, MAPKAPK-1b, MRX19, Ribosomal S6 kinase 2, RSK-2, p90-RSK 3, p90RSK3, RSK, RSK2, S6K-alpha-3, S6K-alpha3, CLS, ISPK-1, MAPKAPK1B, p90-RSK2, Pp90RSK2
Gene ID 6197
UniProt P51812
Pathways MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
Application Notes Approved: IHC, IHC-P (20 μg/mL), IP, WB (1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 20 μg/mL.
Comment

Target Species of Antibody: Mouse

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer PBS,  pH 7.2, 50 % glycerol, 0.09 % azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice avoid freeze thaw cycles. For maximum product recovery, after thawing, centrifuge the product vial before removing cap.
Storage 4 °C,-20 °C
Storage Comment Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. For maximum product recovery, after thawing, centrifuge the product vial before removing cap.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) (AA 604-617) antibody (ABIN462362) Human Pancreas (formalin-fixed, paraffin-embedded) stained with RPS6KA3 antibody ABIN...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) (AA 604-617) antibody (ABIN462362) Human Tonsil (formalin-fixed, paraffin-embedded) stained with RPS6KA3 antibody ABIN46...
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