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HLA-E antibody (Biotin)

HLA-E Reactivity: Human FACS Host: Mouse Monoclonal MEM-E-07 Biotin
Catalog No. ABIN487313
  • Target See all HLA-E Antibodies
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    Reactivity
    • 67
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 44
    • 24
    Mouse
    Clonality
    • 46
    • 22
    Monoclonal
    Conjugate
    • 31
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLA-E antibody is conjugated to Biotin
    Application
    • 42
    • 27
    • 19
    • 13
    • 13
    • 12
    • 9
    • 7
    • 3
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    This antibody recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on many types of the human cells. The published results revealed that the antibody cross-reacts with some classical MHC Class I molecules (MHC Class Ia): HLA-B7 (strongly), HLA-B8 (moderately), HLA-B27, -B44 (weakly).
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Characteristics
    Synonyms: HLA-6.2, HLAE, MHC class I antigen E, HLA class I histocompatibility antigen, alpha chain E
    Immunogen
    Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide
    Clone
    MEM-E-07
    Isotype
    IgG1
    Top Product
    Discover our top product HLA-E Primary Antibody
  • Application Notes
    Flow cytometry: 2 μg/mL as starting dilution.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing andthawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    Abstract
    HLA-E Products
    Synonyms
    EA1.2 antibody, EA2.1 antibody, HLA-6.2 antibody, MHC antibody, QA1 antibody, major histocompatibility complex, class I, E antibody, HLA-E antibody, PATR-E antibody
    Background
    Synonyms: HLA class I histocompatibility antigen, HLA-6.2, HLAE, MHC class I antigen E, alpha chain E
    Gene ID
    3133
    UniProt
    P13747
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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