ABCE1 antibody (AA 419-599)

Catalog No. ABIN4886410

Product Details anti-ABCE1 Antibody

Target: ABCE1 (ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1))

Binding Specificity: AA 419-599

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCE1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family E member 1(ABCE1) detection. Tested with WB in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family E member 1(ABCE1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: ATP binding cassette subfamily E member 1
Protein Name: ATP-binding cassette sub-family E member 1

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human ABCE1 recombinant protein (Position: K419-D599). Human ABCE1 shares 100% amino acid (aa) sequence identity with mouse ABCE1.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for ABCE1

Target: ABCE1 (ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1))

Alternative Name: ABCE1 (ABCE1 Products)

Synonyms: ABCE1 antibody, DDBDRAFT_0188931 antibody, DDBDRAFT_0191227 antibody, DDB_0188931 antibody, DDB_0191227 antibody, abce1 antibody, MGC69546 antibody, DKFZp469K1416 antibody, ABC38 antibody, OABP antibody, RLI antibody, RNASEL1 antibody, RNASELI antibody, RNS4I antibody, C79080 antibody, Oabp antibody, RNS41 antibody, Rnaseli antibody, wu:fb34c09 antibody, wu:fe47b01 antibody, wu:fi09g07 antibody, zgc:111906 antibody, zgc:56045 antibody, Rns4i antibody, ATP binding cassette subfamily E member 1 antibody, 4Fe-4S ferredoxin, iron-sulfur binding domain-containing protein antibody, ATP-binding cassette sub-family E member 1 antibody, RNAse L inhibitor antibody, RNase L inhibitor antibody, ribosome biogenesis/translation initiation ATPase RLI antibody, ATP-binding cassette, sub-family E (OABP), member 1 antibody, ATP binding cassette subfamily E member 1 S homeolog antibody, ABCE1 antibody, abcE1 antibody, LOC100184673 antibody, LOC100213121 antibody, abce1 antibody, TP04_0855 antibody, PVX_115370 antibody, TERMP_RS03360 antibody, Abce1 antibody, abce1.S antibody

Background: ATP binding cassette E1 (ABCE1, also RNase L inhibitor) is an ATPase found in humans involved in viral assembly. It is a member of the ATP-binding cassette (ABC) transporters superfamily and OABP subfamily. ABCE1 inhibits the action of ribonuclease L. Ribonuclease L normally binds to 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) and inhibits the interferon-regulated 2-5A/RNase L pathway, which is used by viruses. ABCE1 heterodimerize with ribonuclease L and prevents its interaction with 2-5A, antagonizing the anti-viral properties of ribonuclease L, and allow the virus to synthesize viral proteins. It has also been implicated to have an effect in tumorcell proliferation and antiapoptosis.

Synonyms: ABC 38 | ABC38 | ABCE 1 | ABCE1 | HuHP 68 | HuHP68 | OABP | Ribonuclease 4 inhibitor | Ribonuclease L inhibitor | RLI | RNase L inhibitor | RNASEL1 | RNASELI | RNS 4I | RNS4I | P61221

Gene ID: 6059

UniProt: P61221