GNB1 antibody (N-Term)

Catalog No. ABIN4886607

Product Details anti-GNB1 Antibody

Target: GNB1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1))

Binding Specificity: AA 2-42, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1(GNB1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequence: SELDQLRQEA EQLKNQIRDA RKACADATLS QITNNIDPVG R

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1(GNB1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: G protein subunit beta 1
Protein Name: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human GNB1 (2-42aa SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGR), identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for GNB1

Target: GNB1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1))

Alternative Name: GNB1 (GNB1 Products)

Synonyms: gnb1 antibody, wu:fb50b09 antibody, wu:fj94h04 antibody, AA409223 antibody, C77571 antibody, Gnb-1 antibody, XGB1 antibody, xgbeta1 antibody, GNB1x antibody, fb39f01 antibody, gnb1l antibody, wu:fb39f01 antibody, wu:fb98e06 antibody, wu:fj09d12 antibody, zgc:55774 antibody, G protein subunit beta 1 antibody, guanine nucleotide binding protein (G protein), beta polypeptide 1a antibody, guanine nucleotide binding protein (G protein), beta 1 antibody, guanine nucleotide binding protein (G protein), beta polypeptide 1 S homeolog antibody, guanine nucleotide binding protein (G protein), beta polypeptide 1b antibody, GNB1 antibody, gnb1a antibody, Gnb1 antibody, gnb1.S antibody, gnb1b antibody

Background: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 is a protein that in humans is encoded by the GNB1 gene. Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene uses alternative polyadenylation signals.

Synonyms: G protein beta 1 subunit | GBB1 | gnb1 | P62873

Gene ID: 2782

UniProt: P62873

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome