FNDC5 antibody

Catalog No. ABIN4889297

Product Details anti-FNDC5 Antibody

Target: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNDC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: Reacts with human Irisin

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): Cross react with mouse, ratIrisin due to 100 % sequence homology.

Purification: Purified (protein A)

Immunogen: Synthetic peptide derived from human Irisin

Application Details

Application Notes:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
IF1:200 - 1:2000 WB : 1:500 - 1:5000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for FNDC5

Target: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Alternative Name: Irisin (FNDC5 Products)

Synonyms: FRCP2 antibody, irisin antibody, 1500001L03Rik antibody, AI836596 antibody, C87088 antibody, PeP antibody, Pxp antibody, fndc5 antibody, si:dkey-264p5.1 antibody, zgc:158684 antibody, fibronectin type III domain containing 5 antibody, fibronectin type III domain containing 5b antibody, FNDC5 antibody, Fndc5 antibody, fndc5b antibody

Background: Mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA

Gene ID: 252995

UniProt: Q8NAU1

Pathways: Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation