MTOR antibody (Mechanistic Target of Rapamycin (serine/threonine Kinase)) (Internal Region)

Details for Product anti-FRAP1 Antibody No. ABIN4889510, Supplier: Log in to see
Antigen
  • FRAP1
  • FRAP
  • FRAP2
  • RAFT1
  • RAPT1
  • 2610315D21Rik
  • AI327068
  • Frap1
  • flat
  • frap1
  • tor
  • wu:fc22h08
  • mechanistic target of rapamycin kinase
  • mechanistic target of rapamycin
  • mechanistic target of rapamycin (serine/threonine kinase)
  • MTOR
  • Mtor
  • mtor
Alternatives
anti-Human MTOR antibody for Western Blotting
Epitope
Internal Region
70
31
29
22
21
18
16
15
15
11
7
7
6
5
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
423
228
219
16
8
6
6
6
6
5
4
3
2
1
1
1
Host
Rabbit
373
48
3
Clonality
Polyclonal
Conjugate
This MTOR antibody is un-conjugated
10
10
9
5
4
4
4
4
4
4
4
4
4
4
4
4
4
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
311
165
131
72
65
52
36
21
16
8
8
7
3
3
3
2
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Synthetic peptide derived from internal part of human mTOR protein
Specificity Reacts with humanand mouse mTOR protein
Purification Purified (protein A)
Plasmids, Primers & others Plasmids, Primers & others MTOR products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Serine/threonine-Protein Kinase mTOR (FRAP1 Antibody Abstract)
Background Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2).
Gene ID 2475
UniProt P42345
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events
Application Notes

Working dilution: Optimal dilutions should be determined by the end user.

Restrictions For Research Use only
Format Lyophilized
Reconstitution Must be reconstituted in distilled water.
Concentration 1 mg/mL
Buffer Tris 0,1M, glycine 0,1M, sucrose 2 %
Storage 4 °C/-20 °C
Storage Comment Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
Expiry Date 24 months
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